The FDA recently released an alert warning consumers about the possible health effects of using tianeptine, an unapproved drug in the U.S. Although other countries have approved tianeptine to treat depression and anxiety, some have restricted how tianeptine is prescribed or dispensed, or revised the drug label to warn of possible addiction. Cases described in medical journals, in calls to U.S. poison control centers, and in reports to the FDA, suggest that tianeptine has a potential for misuse, and people with a history of opioid use disorder or dependence may be at particular risk when using tianeptine. The FDA says consumers should avoid all products containing tianeptine, including those claiming to treat an ailment or disorder.
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